Welcome to the Duren Lab

We are a computational biology research group at the Clemson University Center for Human Genetics. Our aim is to explore and understand the regulatory mechanisms of non-coding DNA. The long-term research goal is to answer the key scientific question” How non-coding genetic variant act through context specific gene regulatory network to influence phenotype”.

To this end, we develop novel computational tools for integrative analysis of genomics data to infer gene regulatory networks, to detect heterogeneity, and to annotate the regulatory function of genetic variants by context specific manner. (see Research).

We are part of the Clemson University Center for Human Genetics, which is located in Self Regional Hall, a state-of-the-art research and educational facility located in Greenwood, South Carolina.

We are looking for new Postdocs, graduate students, and ungraduate students to join the team (more info) !


12 April 2024

The Linger is published on Nature Biotechnology . Congrats Qiuyue.

12 April 2024

We are reported on Clemson News , Go Tigers!

29 March 2024

Zhana visited the Center for Computational Biology and Bioinformatics at the Indiana University and presented the LINGER method at the seminar.

22 March 2024

We attended the MCBIOS2024 conference, which Zhana co-organized. Zhana and Ishita gave talk presentations. Naqing and Hui presented posters.

15 March 2024

We recived 2 Years R21 fund from NIDA/NIH, direct cost $275K!

15 March 2024

Zhana served on the review panel of data integration and statistical analysis methods for dGTEx!

1 Feb 2024

Zhana served as a councilors for NIGMS/NIH concil meeting.

26 Oct. 2023

Zhana visited the Department of Genetics at the Washington University in St. Louis and presented the LINGER method at the seminar.

8 Sept. 2023

We recived 5 Years R35 fund from NIGMS/NIH, direct cost $1.25M!

... see all News