Welcome to the Duren Lab

We are a computational biology research group at the Clemson University Center for Human Genetics. Our aim is to explore and understand the regulatory mechanisms of non-coding DNA. The long-term research goal is to answer the key scientific question” How non-coding genetic variant act through context specific gene regulatory network to influence phenotype”.

To this end, we develop novel computational tools for integrative analysis of genomics data to infer gene regulatory networks, to detect heterogeneity, and to annotate the regulatory function of genetic variants by context specific manner. (see Research).

We are part of the Clemson University Center for Human Genetics, which is located in Self Regional Hall, a state-of-the-art research and educational facility located in Greenwood, South Carolina.

We are looking for new Postdocs, graduate students, and ungraduate students to join the team (more info) !


8 Sept. 2023

We recived 5 Years R35 fund from NIGMS/NIH, direct cost $1.25M!

10 July 2023

Zhana named as a member of the Editorial Board of Genome Biology

3 July 2023

Zhana attend the BIRS single-cell Plus conference at Banff, Alberta, Canada and give a talk about GRN from sc-multiome data.

1 Nov. 2022

Funded by the P20 COBRE grant as a research project leader, with a direct cost of $175k/year for four years.

20 Oct. 2022

Zhana served as a reviewer for BDMA study section in NIH.

15 Aug. 2022

Two graduate students Ishita Debnath and Fengge Chang joined our lab!

19 July 2022

The unPairReg is published on Genome Biology . Congrats Qiuyue.

16 May 2022

The scREG is published on Genome Biology . Congrats Cham and Naqing.

12 May 2022

Zhana virtually presented the sc-REG method at the Computational Biology Seminar at the Genentech.

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